Gene therapy · Capsid intelligence
AAV Capsid Intelligence Draft
Geometry/topology resolves capsid siblings that pooled protein-language-model embeddings cannot — the discriminative-signal result underlying the topology-emulator architecture (provisional US 63/986,270).
→Combination safety + efficacy
IO+TKI Toxicity & Response Framework In prep
Population-fragility-dominant toxicity prediction and max-of-arms × synergy efficacy logic, validated across CLEAR / KN-775 / LEAP-002 / LEAP-012. Manuscript in preparation.
Methodology
AI-Native Discovery Intelligence In prep
The multi-agent, audit-disciplined methodology behind the platform — pre-registration, cross-tool consensus, and provenance-gated benchmarking. Methods paper in preparation.
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